Investment Details

NATCO Pharma Limited is investing US$ 14 million in eGenesis, Inc. through its wholly owned subsidiaries:

  • NATCO Pharma (Canada) Inc.: US$ 9.5 million
  • NATCO Pharma South Africa Proprietary Limited: US$ 4.5 million

Investment Instrument: Convertible promissory notes with 8% interest rate compounded annually

Previous Investment: In 2024, NATCO had invested US$ 8 million in eGenesis through preferred stock

Total Investment: US$ 22 million

Completion Timeline: September 30, 2026

Consideration: Cash consideration

Target Company Background

Industry: Biotechnology

Incorporation Date: October 1, 2015

Business Focus: Using multiplex gene editing and genome engineering platform to develop safe and effective transplantable organs

Key Business Activities:

  • Addressing cross-species molecular incompatibilities and viral risk via genetic engineering
  • Developing porcine solid organ donors for human transplantation
  • Current clinical trials for porcine kidney transplantation and porcine liver perfusion
  • Clinical stage company (pre-revenue)

Recent Milestone: In March 2024, eGenesis announced the world's first porcine kidney transplant in a living patient under FDA's Expanded Access pathway, followed by two additional patients with exceptionally positive outcomes

Geographic Presence: United States of America (headquartered in Cambridge, Massachusetts)

Strategic Rationale

The investment aims to support "new-age therapeutic programmes addressing critical unmet medical needs" in organ transplantation. eGenesis is pioneering genome engineering-based approaches to end the global organ shortage and transform the treatment of organ failure through their EGEN™ Platform.

Regulatory and Transaction Details

Related Party Transaction: No

Governmental/Regulatory Approvals Required: None specified

Percentage of Shareholding/Control: No additional shares being acquired at time of completion (convertible notes)