Milestone Achievement

Zydus Hospital, Ahmedabad announced crossing 300 liver transplants, the highest count in Gujarat.

Clinical Scope

The liver transplant programme encompasses living‑donor, deceased‑donor, ABO‑incompatible, paediatric, and simultaneous liver‑kidney transplants. Approximately 40 % of patients present with acute‑on‑chronic liver failure and require transplantation within 24‑36 hours of admission.

Notable Cases

  • A 12‑year‑old boy from Junagadh with acute liver failure was stabilized after removal of necrotic liver tissue and successfully transplanted; his mother acted as donor.
  • A 22‑year‑old architecture student with acute liver failure and mismatched donor underwent rituximab‑free continuous plasma exchange, splenectomy and liver transplantation, recovering well.
  • A 37‑year‑old lean‑NASH patient air‑lifted from Chandigarh, weighing 43 kg, was treated for infection and muscle loss before transplant; he has been disease‑free for two years.
  • A 50‑year‑old man from Raipur with autosomal dominant polycystic kidney disease required simultaneous liver‑kidney transplantation, including removal of a large infected liver cyst and native kidney.

Multidisciplinary Team & Infrastructure

The team is led by Dr. Anand Khakhar, a liver transplant and HPB surgeon with over 25 years experience and a Dr. B.C. Roy Award recipient, and Dr. Yash Patel, liver transplant surgeon. Supporting specialists include hepatologists, gastroenterologists, nephrologists, anaesthetists, critical‑care physicians, radiologists, nutritionists and rehabilitation experts. Facilities feature modular advanced operating theatres, dedicated liver ICUs, advanced MRI, FibroScan imaging, and comprehensive immunosuppression protocols. Pre‑transplant antibody reduction is achieved with rituximab and plasma exchange where tolerated.

Donor Safety & Regional Context

In South‑East Asia, roughly 80 % of liver transplants are from living donors. Zydus Hospital emphasizes donor safety, aiming for donors to return home in good health without impeded recovery. The hospital also engages in community awareness to increase living‑donor participation.

Disease Burden Context

Non‑alcoholic fatty liver disease (NAFLD) now affects one in four adults in India, progressing to NASH, cirrhosis or liver cancer if untreated, driving demand for transplant services.

Conclusion

The achievement underscores Zydus Hospital’s capability to deliver complex, multidisciplinary liver transplant care and positions it as a leading transplant centre in Gujarat.