Spot gold slipped 0.8% to $4,782.74/oz and futures 0.6% to $4,802.49/oz by 06:15 ET.
A firmer U.S. dollar, up 0.2% against peers, and higher oil prices from Strait of Hormuz closure pressured gold.
Investors await Senate Banking Committee hearing of Fed Chair nominee Kevin Warsh at 10:00 ET, amid concerns over Fed independence.
The U.S.-Iran ceasefire, announced by President Donald Trump on April 7, is set to expire later this week, adding geopolitical uncertainty.