Iranian Foreign Minister Abbas Araghchi and Parliament Speaker Mohammad‑Bagher Ghalibaf will lead a delegation arriving Friday night in Islamabad.
The US will send Vice President JD Vance, envoy Steve Witkoff and Jared Kushner for Saturday talks to secure a lasting ceasefire.
Talks aim to turn Tuesday's fragile ceasefire into a durable peace, while Israel continues military actions in Lebanon against Hezbollah.
Outcome remains uncertain; US‑Iran disagreement includes the virtual closure of the Strait of Hormuz as a key issue.